The side effects depend on the type of treatment you use. Generally, for topical, over-the-counter creams, you can watch out for stinging, redness, irritation and peeling — these side effects usually don’t go any deeper than the skin. Others, like oral antibiotics or hormonal medications, could come with new sets of complications, so we suggest talking to your doctor before pursuing the treatment.
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
Minocycline is available in generic form or the branded formulation, Solodyn. The most-prescribed oral antibiotic acne medication for moderate to severe inflammatory acne like cystic acne, Solodyn is a minocycline like those mentioned above. However, it comes in an extended release formula that allows it to work to clear skin over the course of the day with just one daily dose.
The two laser treatment options above are great for acne scar removal, but aren't generally recommended as acne treatment. If you're still experiencing active acne breakouts and wondering how to get rid of acne with laser treatments, check out photodynamic therapy. It combats active moderate to severe acne while also diminishing older acne scars by using light energy to activate a powerful acne-fighting solution. Patients may require 2 or 3 treatments over several weeks and should expect some redness, peeling and sun sensitivity. This treatment will cost between $2000 to $3500 per series.
Contrary to the marketing promises of “blemish banishers” and “zit zappers,” immediate results are not the trademark of acne treatments — a frustrating truth to anyone suffering through a breakout. And while pimples are personal (your stress-induced spots will look and act differently than your best friend’s breakout), the best acne treatments will include a regimen of products to hit all of acne’s root causes. We tested 43 kits to find the most well-rounded breakout-fighting solutions on the market.

Topical antibiotics deemed safe during pregnancy include clindamycin, erythromycin, and metronidazole (all category B), due to negligible systemic absorption.[47][137] Nadifloxacin and dapsone (category C) are other topical antibiotics that may be used to treat acne in pregnant women, but have received less study.[47][137] No adverse fetal events have been reported from the topical use of dapsone.[137] If retinoids are used there is a high risk of abnormalities occurring in the developing fetus; women of childbearing age are therefore required to use effective birth control if retinoids are used to treat acne.[20] Oral antibiotics deemed safe for pregnancy (all category B) include azithromycin, cephalosporins, and penicillins.[137] Tetracyclines (category D) are contraindicated during pregnancy as they are known to deposit in developing fetal teeth, resulting in yellow discoloration and thinned tooth enamel.[1][137] Their use during pregnancy has been associated with development of acute fatty liver of pregnancy and is further avoided for this reason.[137]
The other downside to Proactiv+ is that the bottles are small — like, half the size of Paula’s Choice small. Combine that with its recommended two or three-times daily application, and you’re going to be going through a lot of kits, which ultimately means spending more money on your treatment. If Proactiv is the only thing that works for you, it may very well be worth the investment, but we recommend starting with Paula’s Choice to see if you can get the same results at a cheaper price.

For UVA protection, a sunscreen with a high UVA protection of PA+++ or higher of PA++++ as recommended, especially to treat PIE. PPD is the UVA equivalent of SPF; use a sunscreen with a minimum of PPD20. The PA+ system has a + that corresponds to a tier of PPD protection. Of note, different countries use different PA systems. Japan and Taiwan changed their PA system to a 4+ tier system while Korea uses a 3+ tier system.
The relationship between diet and acne is unclear, as there is no high-quality evidence that establishes any definitive link between them.[52] High-glycemic-load diets have been found to have different degrees of effect on acne severity.[7][53][54] Multiple randomized controlled trials and nonrandomized studies have found a lower-glycemic-load diet to be effective in reducing acne.[53] There is weak observational evidence suggesting that dairy milk consumption is positively associated with a higher frequency and severity of acne.[51][52][53][55][56] Milk contains whey protein and hormones such as bovine IGF-1 and precursors of dihydrotestosterone.[53] These components are hypothesized to promote the effects of insulin and IGF-1 and thereby increase the production of androgen hormones, sebum, and promote the formation of comedones.[53] Available evidence does not support a link between eating chocolate or salt and acne severity.[52][55] Chocolate does contain varying amounts of sugar, which can lead to a high glycemic load, and it can be made with or without milk. Few studies have examined the relationship between obesity and acne.[2] Vitamin B12 may trigger skin outbreaks similar to acne (acneiform eruptions), or worsen existing acne, when taken in doses exceeding the recommended daily intake.[57] Eating greasy foods does not increase acne nor make it worse.[58][59]
Rosemary oil has been around for years and used topically for acne and inflamed skin. (15) A Chinese study concluded that rosemary essential oil helps decrease acne due to its antibacterial effects. To better understand the effects, the study increased the concentration of the rosemary essential oil, resulting in severely damaged bacterial bodies. Treated bacteria eventually led to bacterial death. (16) 

It’s no surprise that coconut oil may help since it’s so useful in just about anything. But there is a reason for this. Coconut oil contains properties that encourage the elimination of bacteria, which is why there are so many uses of coconut oil for skin. Lauric acid is the main ingredient in coconut oil, and this acid that makes it an effective treatment against acne because it provides antibacterial results. (17)  
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Because baby acne typically disappears on its own within several months, no medical treatment is usually recommended. If your baby's acne lingers for much longer, your baby's doctor may recommend a medicated cream or other treatment. Don't try any over-the-counter medications without checking with your baby's doctor first. Some of these products may be damaging to a baby's delicate skin.
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Antibiotics. These work by killing excess skin bacteria and reducing redness. For the first few months of treatment, you may use both a retinoid and an antibiotic, with the antibiotic applied in the morning and the retinoid in the evening. The antibiotics are often combined with benzoyl peroxide to reduce the likelihood of developing antibiotic resistance. Examples include clindamycin with benzoyl peroxide (Benzaclin, Duac, Acanya) and erythromycin with benzoyl peroxide (Benzamycin). Topical antibiotics alone aren't recommended.
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